And the fun is going on!

From climate-sceptics to Jean Staune and from Jean Staune to Vincent Fleury and his blog, where I found that!

Followed the links to:

Pathetic CNRS guy is still pathetic!

[edit] more…


Oops 090614#1

Snakes follow lizards, in evolution [48,99]. However, many snakes still have vestigial limbs (boa, python [49]).

Reference 491 is incorrectly cite here; could be reference 48b2 instead.

It’s a pity that Fleury don’t present Cohn & Tickle’s [48b] and Cohn et al. [48a]3 in his discussion of limb positioning and specification.

1. Tbx3 can alter limb position along the rostrocaudal axis of the developing embryo, Charalampos Rallis, Jo Del Buono and Malcolm P. O. Logan, Development 132, 1961-1970 2005 doi:10.1242/dev.01787

2. Developmental basis of limblessness and axial patterning in snakes, Martin J. Cohn and Cheryll Tickle, Nature Volume 399, 1999 doi:10.1038/20944

3. Hox9 genes and vertebrate limb specification, Cohn MJ, Patel K, Krumlauf R, Wilkinson DG, Clarke JD, Tickle C., Nature. 1997 May 1;387(6628):97-101, doi:10.1038/387097a0

The invertebrate morphogenesis

The invertebrate morphogenesis

The second section of Fleury’s paper is about The invertebrate morphogenesis and the example chosen is Drosophila the fly, which is the most studied of the invertebrates but far from describing the “invertabrates” morphogenesis in general, just take a look at a sponge. Two subsections, The fly bauplan and The homeobox genes.

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Abstract The origin of tetrapods is a c…



The origin of tetrapods is a complex question that webs together genetic, paleontological, developmental and physical facts. 

A very interesting question of evolutionary biology indeed, mobilizing the efforts of many.


Basically, the development of embryos is described by a complex mix of mechanical movements and biochemical inductions of genetic origin. 

It is difficult to sort out in this scientific question what are the fundamental features imposed by conservation laws of physics, and by force equilibria, and what can be ascribed to successive, very specific, stop-and-go inductions of genetic nature.

Is it a difficult question ? From zygotes you can get individuals with no appendages or with four, six, eight, ten or many (myriapods). It is quite easy to identify what differentiate them: genomes. Genomes which specify the entire spectrum of physico-chemical properties of every part of the developing embryo, as well of the formed individual throughout its existence, in interaction with the environment. And these physico-chemical properties specify every aspect of cellular displacements from zygote to death, including embryogenesis.
That’s the easy part, easy enough for everybody to understand, even if he isn’t a specialist.
It’s much more difficult to understand the mechanisms in detail. And that’s the fun part.


A posteriori, evolution selects the parameters of this process as found in the observed species. 

There is a huge misunderstanding of the term “evolution”. Fleury seems to be allergic to the notion of Natural Selection and, as he say, is preoccupied by Evolution not Natural Selection, ignoring the mechanisms known to operate in biological evolution.
The persistence of such an error in the abstract of the paper calls a question: did an evolutionary (or evo-devo) biologist reviewed the paper? I hope the answer is no. I hope that no biologist reviewed the paper.

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It seems that the European Physical Jour…

It seems that the European Physical Journal – Applied Physics inaugurates a new field of papers dealing with applied physics on biological subjects. The inaugural paper by Vincent Fleury deals with tetrapod’s embryogenesis.

As the author and the author’s views on biological evolution and Darwinism have been of interest for me the last two years, I’ll take a closer view of the paper and post here my notes.

I was expecting a publication to a generalist or biology-centered, Open Access and providing discussion space, journal, thus I’m disappointed, but not surprised, to see the paper in a journal which doesn’t have expertise on the evo-devo domain. I wonder how the reviewers were selected and who of the editorial team handled the paper.

This blog may be used to complement the lack of discussion space associated with the paper. Please, read the About page before deciding to comment.

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Just another Oldcola’s blog 😉