A funny side-effect of PZ Myers “An ontogeny of toilet drain behavior” was to bring Fleury’s theory within the range of one of the famous crackpot detectors, Suzan Mazur.
This is a completely different dimension from my favorite local (French) crackpot detector, Jean Staune, the very anti-Darwin Secratary General of the Université Interdisciplinaire de Paris, an association heavily financed by the John Templeton Foundation. Whatever Jean likes (in science) becomes immediately suspicious and it was Jean who introduced Fleury in a public forum, where we first meet.
Now, Suzan Mazur, spotted Fleury, and he grabbed the opportunity to explain himself to a larger audience. That’s great, the visibility is much wider then an isolated blogger in France could expect trying to debunk Fleury’s theory.
As I acknowledged, I’m the one who asked PZ Myers’ opinion on Fleury’s paper. The choice of the science blogger to contact at first was easy to make. PZ is an embryologist, have a particular interest for integration of developmental and evolutionary biology, he is a longtime fan of d’Arcy Thompson, is rather outspoken, it’s difficult to influence him, and he have a large audience with a fair proportion of scientists who dare speak their minds in the comments.
I was delighted with PZ’s conclusions which match mines closely, and as a bonus Fleury abundantly commented making his point of view much clearer then in his paper, so people know better where he stands.
In the interview Suzan Mazur stupidly try to make her point that evolutionary biologists, biologists in general, PZ in particular, are worried about some paradigm shift. Paradigms shifts may be a common topic of interest of crackpot detectors and crackpots. PZ took care of that part of the interview.
Fleury’s opinion about PZ is a complex subject:
Summarizing: he promotes good science, with reviews which are OK, except it’s rubbish, and he isn’t trustworthy. Shifting position during a single interview! Who’s the guy with the weird behavior here?
Let’s go for the more scary thingies:
I would like to thank Suzan Mazur for her excellent idea to interview Fleury, another way to help a fellow hang himself. And Fleury for accepting; quite difficult to translate everything he said in the french press and radio, but now we have an english version of the Big Picture.
1. For Fleury “creationism” is a term restricted to YECreationism.
2.
It may be asked how far I extend the doctrine of the modification of species. The question is difficult to answer, because the more distinct the forms are which we may consider, by so much the arguments fall away in force. But some arguments of the greatest weight extend very far. All the members of whole classes can be connected together by chains of affinities, and all can be classified on the same principle, in groups subordinate to groups. Fossil remains sometimes tend to fill up very wide intervals between existing orders. Organs in a rudimentary condition plainly show that an early progenitor had the organ in a fully developed state; and this in some instances necessarily implies an enormous amount of modification in the descendants. Throughout whole classes various structures are formed on the same pattern, and at an embryonic age the species closely resemble each other. Therefore I cannot doubt that the theory of descent with modification embraces all the members of the same class. I believe that animals have descended from at most only four or five progenitors, and plants from an equal or lesser number.
Analogy would lead me one step further, namely, to the belief that all animals and plants have descended from some one prototype. But analogy may be a deceitful guide. Nevertheless all living things have much in common, in their chemical composition, their germinal vesicles, their cellular structure, and their laws of growth and reproduction. We see this even in so trifling a circumstance as that the same poison often similarly affects plants and animals; or that the poison secreted by the gall-fly produces monstrous growths on the wild rose or oak-tree. Therefore I should infer from analogy that probably all the organic beings which have ever lived on this earth have descended from some one primordial form, into which life was first breathed.
(Charles Darwin, 1959)
to the ” isolated blogger ” : the word paradigm shift appears explicitely in the website of the CNRS, about the determination of plant morphogenesis by mechanical fields, and related work along such lines:
http://www2.cnrs.fr/presse/communique/1485.htm
best wishes, “isolated blogger”‘
Once I have finished with cteappv Fleury I’ll certainly take a look at that.
Don’t loose time with other peoples work, it doesn’t validate your.
Concentrate to explain your bugs, if possible. Plenty of them.
not only you have already sunk completely my poor old chap, but you have carried Dr Myers in your sinking.
Part of the comment erased for non observance of the blog’s rules: “the blog’s language is english ; comments in any other language will be discarded” – “comments out of focus (say, regarding my private life) will be discarded”
Comment erased for non observance of the blog’s rules: “the blog’s language is english ; comments in any other language will be discarded”
You are welcome to discuss science here Dr Fleury, observing the rules.
Nothing else.
You do not understand science M. Vekris
it took you 2 years to just see that there is a flow forming around the presumptive navel a hyperbolic flow with streamlines oriented caudally, and streamlines oriented rostrally. Had I only seen that, modeled it, and dragged the attention towards this, that would suffice to justify my entire scientific work, and all your comments against me are, in view of that, compeltely mediocre and unfair.
that shakes the entire picture of body development. Instead of understanding this you keep on defamating and trying to introduce archane subtleties about the nature of the flow etc.
You sent the paper to Dr Myers, to discover what : Dr Myers is completely unaware of the existence of vortices in embryo development. How ridicule. I cannot believe he is a scientist. Oh dear, and he holds a blog?, and pontifies all the time? How ridicule. How can he dare speak of science and comment papers?
At least you have learnt, thanks to me, that these vortices existed,and you know a bit more than him : see, I am ready to make a compliment, you need not sent the paper to Myers, you know more of the topic than him.
You are not doing science here. If you were, you would do this from your lab, where you would immediately be stopped. Everything I talk about is published in articles, and reproduced on my personal university website, and nobody around me complains. I have the support of the CNRS, as you know from the lawyers.
Please sent the comments to EPJ, and I will correct the errors, there are certainly a few.
The habilis-erectus distinction for what I see is ridiculous considering what is discussed
Everything you say around the 2 or 4 vortices is rubbish
Evrything you say about the lateral plate is rubbish, and a fruit of your hate, and Myers, who says the same thing is just an ignorant.
A few references have skipped during the editorial process due to length of the paper, fair enough
etc.
The segmentation thing, which is very small in my paper, is certainly not invalidated, I was just raising a concern about the discrepancies in the literature.
I disagree with what you say about Darwin.
etc. etc.
Your aim, here is not to discuss, it is to set an unfair trial, entirely of your own by the way, as you state yourself, you are isolated, and even lonely. These manners are just yours, scientists do not do that, and when they do, like Myers and you, they just sink, as they show how little they know of the true, leading edge science.
Dr Fleury,
I will be kind and assume that you have a short memory span (less than 2 years) and I’ll refresh it.
We discussed those caudally directed cellular flows almost two years ago and here is the link to your explanations.
You failed to show the presence of the two vortices termed L2/R2 displayed at the time on your website of the University of Rennes.
I repeat to help you cope with your memory problems, that my question was originally asked because I wanted to see how those L2/R2 was related with the hindlimb field.
There is no experimental evidence of the L2/R2 vortices still today. You must be aware of that. And if some day you are able to show that those vortices are not imaginary, it will be time to take a look at how they relate with the hindlimb morphogenic fields.
So, don’t come tell me:
spend your time to show them these two vortices to complete your schema.
I already explained that the critics of your theory, especially the lack of experimental data confirming crucial points of it, has nothing to do personally with you.
I sent the paper to an embryologist, friendly to the integration of biological structuralism in the evodevo domain, his specialty, to have a review by a biologist, suspecting that EPJ AP didn’t addressed it to one specialist of the field for review. Am I wrong on that? I was isolated, it’s not anymore the case. I’m really grateful to PZ Myers for spending his time with your paper.
I’m not doing science here, I just comment on a dreadful paper which should be an embarrassment for you, the journal that accepted it, and maybe your colleagues. Not many of them to support you on Pharyngula, isn’t it?.
A few errors? Are you joking and I don’t get it? Misreporting so badly a paper and driving conclusions could you call that fair enough? Confusing proteins with mRNAs, in situ hybridization with cartilage staining, comparing different developmental stages and driving conclusions without checking the controls, seeing fin buds adjacent to the telencephalon of the control and driving conclusions about the mutant, driving conclusions about the way genes expression regulation is related to pressure without data. What’s the relation with:
You are kidding us Dr Fleury, aren’t you?
OK, that was funny. As much funny as this one:
Let’s be serious, starting with an easy one:
You may disagree as much as you want and it will help your exposé‘s credibility to read and comment about the use of the term “archetype” by Darwin, give as the references of the pages where “scaffold” is used and “arbitrary” lengths are mentioned. This would be a nice use of this discussion space to support your opinions. Open Access CC-license & discussion possible; easy to post links.
Realy?
You must know that I don’t give a shit about what is published in personal university websites, but maybe you are a groupie of Michael Behe because his non-sense is reproduced in his personal university website; do you?
Neither I give a shit of what is published in scientific journals if it’s rubbish.
A link for “Confusing proteins with mRNAs”?
so, I am right? You keep on not seeing these flows as important? Youd had not seen them before at all, before jumping on me; Wetzel did not see the caudal flow, the contemporary researchers did not see them, nor model them correctly, and despite all my weaknesses in biology, I was able to see that and model it correctly?
How cool.
So you see, a man’s errors are his portals of discovery (James Joyce).
so cool.
Dr Fleury,
mesoderm cells moving caudally, say to form extra-embryonic tissues, clearly depicted, in a completely different flow pattern then the one you claim (vortices), can’t be considered as validating the presence of vortices centered at the hindlimb fields.
So for the moment you are dead wrong.
Still “how cool”?
oh a simple example about the word “arbitrary”, it is a problem of double translation, the original text writes twice “to any extent”
“to any extent” doesn’t fit with “arbitrary”, bad translation? from english to english?
A lot of people are interested, it’s a metric equivalent to the impact factor
ahem :
ARCHETYPAL
Of or belonging to the Archetype, or ideal primitive form upon which all the beings of a group seem to be organised.
Origin of species, glossary
And the definition is the last common ancestor presenting the traits considered, right?
that can continue for ever you know “ideal primitive form” “general pattern”, that is what we are dealing with, and I can model it. So cool.
And as stated (somewhere) by Darwwin, the archetype has a complete plan, and the other animals are formed by stretching the limbs to “any extent”, which is synonymous of “to an arbitrary length”
give us the statistics of visit of this very site, if it is so interesting.
Your remark about the mesodermal cells is so ridiculous : you are already talking about the cells flowing away, the discrepancy between the flows I show in the paper and the true “away” flow is small and related to the fact that cells also flow through the U turn of the primitve streak, it is very simple to add that, but you do not master these things. You prefer to ironize and track unsignificant errors, without seeing the problem in depth; my model is ok for that too, do not worry. The body of the embryo forms from cells coming in. You really do not understand anything to the formation of tetrapods.
Please send comments along these lines to EPJ, do not forget. Make my day.
Let me finish first my review and I’ll write an Open Letter to the editor-in-chief of EPJAP 😉
Until you have new data available validating the presence of L2/R2 and their relationship with the hindlimb morphogenic field (embryologists definition), I’ll just keep linking to the anniversary of the missing vortices.
Just to avoid loosing time stupidly and go on to finish with the paper .
In the mean time maybe you can explain your jokes.
Comment erased for non observance of the blog’s rules: “the blog’s language is english ; comments in any other language will be discarded”
you are pathetic, Vekris. You should stop;